Eur Rev Med Pharmacol Sci 2012; 16 (3): 351-354

Correlation between oxidative stress and antioxidant defence in south indian urban vegetarians and non-vegetarians

M.S. Somannavar, M.V. Kodliwadmath*

Department of Biochemistry, J.N. Medical College Belgaum, KLE University, Karnataka (India) *Department of Biochemistry, Navodaya Medical College, Raichur, Karnataka (India)


Background and Objectives: The diet is a key environmental factor implicated in health and disease. Oxidative stress, antioxidant status and their relation to diet is a subject of interest in recent years. The objective of the study was to compare lipid peroxidation and antioxidant status in healthy vegetarians and non-vegetarians.

Methods: The present study comprises100 healthy individuals (50 vegetarians and 50 non-vegetarians) residing in Belgaum urban area. All the participants were in the age group of 40-60 years of both sexes. This cross-sectional study was done in one year period from April 2007 to March 2008. Malondialdehyde (MDA) (lipid peroxidation product) was estimated by thiobarbituric acid method, glutathione peroxidase by Beutler’s method, Vitamin A and Vitamin E by Bessay et al and Quife et al methods respectively.

Results: Our study revealed that the blood MDA level was significantly increased (p value < 0.001) in non-vegetarians compared to lacto-vegetarians and lacto-ovo-vegetarians. There was significant decrease in the level of enzymatic antioxidant glutathione peroxidase and non-enzymatic antioxidants Vitamin A and Vitamin E in non-vegetarians compared to lacto-vegetarians and lacto-ovo-vegetarians (p value < 0.001).

Conclusions: Results of the present study indicate that there was an increased lipid peroxidation and a low antioxidant status in non-vegetarians compared to vegetarians. Vegetarian nutrition provides adequate antioxidants which effectively prevent free radical generation.

Corresponding Author: Manjunath. S. Somannavar, MD; e-mail: manjunathsomannavar@gmail.com

To cite this article

M.S. Somannavar, M.V. Kodliwadmath*
Correlation between oxidative stress and antioxidant defence in south indian urban vegetarians and non-vegetarians

Eur Rev Med Pharmacol Sci
Year: 2012
Vol. 16 - N. 3
Pages: 351-354