Clinical analysis of 59 children with hand foot and mouth diseases due to enterovirus EV71 and concomitant viral encephalitis

M.-G. Wang, H.-M. Sun, X.-M. Liu, X.-Q. Deng

Department of Neurology, Xuzhou Children’s Hospital, Xuzhou, Jiangsu, China. dengxingqiang1962@163.com

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• Pediatrics

OBJECTIVE: To analyzed the clinical features of children with HFMD and viral encephalitis and to summarize some treatments.

PATIENTS AND METHODS: A total of 59 children with HFMD were included in this study. All children underwent complete blood count, blood biochemical test cerebrospinal fluid examination, chest X-ray and brain MRI.

RESULTS: One child died 24 hours after admission due to central respiratory failure with myocardial damage. After the treatment, 58 children had normal temperature, resolved rash, normal complete blood count, biochemical blood tests and cerebrospinal fluid test, respiratory and circulatory symptoms and signs, as well as neurological symptoms, disappeared. The hospitalization time was 12-21 days. After follow-up for 1-3 months, all children were recovered, and without any severe sequelae.

CONCLUSIONS: HFMD and the complicated viral encephalitis usually occurred in the children < 3 years old. The clinical manifestations were not typical. Monitoring of the child’s clinical symptoms, signs and relevant examinations was required.

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