Meta-analysis of the effects of helmet-assisted non-invasive ventilation in the treatment of acute respiratory failure

X. Zheng, N.-N. Qu, W.-P. Wang, P. Shu, X.-L. Shi, H. Deng, S.-J. Li, Y.-B. Qin

Department of Respiratory, The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, P.R. China. zhengxin33@protonmail.com

---

• Respiratory Medicine

OBJECTIVE: To study the efficacy of helmet-assisted non-invasive ventilation and conventional ventilation in the treatment of acute respiratory failure (ARF).
MATERIALS AND METHODS: Cochrane Library, PubMed, Embase and CNKI databases were searched for randomized controlled trials and case-control trials of helmet-assisted noninvasive ventilation in the treatment of ARF. The outcome measures included respiratory rate, intubation rate, complication rate, mortality rate and arterial blood gas analysis of the commonly used indicators (PaCO2/ PaO2 / pH). The results of the included studies’ odds ratio (OR) and its 95% confidential interval (CI) were analyzed using Stata software.
RESULTS: The results of the analysis showed that the in-hospital mortality, intubation rate and complication rate were all significantly decreased with the p-value less than 0.05, which was statistically significant.
CONCLUSIONS: Helmet-assisted noninvasive ventilation can significantly reduce hospital mortality, intubation rate and complication rate, improving the survival rate and prognosis of patients with ARF.

Free PDF Download