CTAR®system, a hypoxia-induced and targeted anti-aging and repair system on human skin

S. Akiyama

The Japanese Academy of Dermatology (TJAD), Chuo-ku, Tokyo, Japan. info@vsh-lab.jp

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• Dermatology

OBJECTIVE: The effective protection of skin cells and timely repair of damaged ones are of great significance for the maintenance of human skin’s normal functions. Researches on skin cells mainly focus on the functions of repair factors. Relatively few studies have been made to clarify how skin cells sense the environment, absorb and transport nutrients, and achieve self-healing. CTAR®system, a new system, is proposed and demonstrated against human skin aging.

MATERIALS AND METHODS: This study is made based on the research outcomes of the 2013 and 2019 Nobel Prize in Physiology or Medicine: precise regulation of cellular vesicle transport networks, and cellular perception and responding mechanisms to oxygen. The technologies and methods derived from the award-winning theories were applied in the field of skin anti-aging.

RESULTS: It has shown that skin aging is a result of a series of injuries that have not been adequately repaired and then accumulate. The latest research on anti-aging of skin including channel identification, vesicle transport, induced activation, and damage repair has spawned CTAR®system, a hypoxia-induced and targeted anti-aging and repair system.

CONCLUSIONS: We determined that a considerable part of skin aging problems can be partially solved by taking full advantage of the vesicular trafficking system in skin and improving skin’s metabolism levels and physiological functions under low oxygen levels with CTAR®system.

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