Paragangliomas of the carotid body and other rare localisation

M. Marchesi, M. Biffoni, M.O. Jaus, R. Nobili Benedetti, L. Tromba, A. Berni, F.P. Campana

3rd Institute of Clinic Surgery, Department of Surgery, “La Sapienza” University – Rome (Italy)

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• Oncology

Abstract. – Cervical paragangliomas are uncommon benign or malignant neoplasms, originated by stem cells of neural crest. It is not easy nowadays to define properly their biological behaviour, the possible multiple location and the association with Multiple Endocrine Neoplasms. After a wide review about recent diagnostic, pathological and clinical acquisition, authors report their caseload of 10 patients affected by sporadic paragangliomas and 1 by familial multiple neoplasm localised in carotid bodies of both sides, left vagus nerve and left hypoglossus nerve. All patients but one were treated by a curative resection of the neoplasm. In one case only an explorative laparatomy was possible because of the visceral and vascular involvement.