Eur Rev Med Pharmacol Sci 1997; 1 (6): 217-221

Transcutaneous ethanol injection in hepatocarcinoma: Problems in analgesia and sedation

C. Iannarone, M. Caratozzolo, L. Costamagna, A. Fegiz, G. Tellan, I. Baumgartner, A.M.R. Maselli, A. Fantera

Insegnamento di Anestesiologia e Rianimazione, “La Sapienza” University – Rome (Italy)


Abstract. – Therapeutic ethanol injection into primitive or secondary hepatic tumours if performed in “one shot” causes a great deal of pain. For this reason an analgesic/sedation protocol was devised. This relies on the administration of ketorolac-propofol-nitrogen oxide mixture that has been used to treat patients with neoplastic hepatic diseases. A 20 patient series is described. Analgesic protocol was very effective and the only drawbacks were a residual sleepiness than in part is probably dependent on ethanol emigration into the bloodstream and consequently to the central nervous system depression.

To cite this article

C. Iannarone, M. Caratozzolo, L. Costamagna, A. Fegiz, G. Tellan, I. Baumgartner, A.M.R. Maselli, A. Fantera
Transcutaneous ethanol injection in hepatocarcinoma: Problems in analgesia and sedation

Eur Rev Med Pharmacol Sci
Year: 1997
Vol. 1 - N. 6
Pages: 217-221