Eur Rev Med Pharmacol Sci 2023; 27 (3 Suppl): 109-113
DOI: 10.26355/eurrev_202304_31327

Reduction of double chin without surgery using ascorbic acid and ascorbyl-palmitate solution: a clinical study

A. Scarano, R. Amore, A. Greco Lucchina, E. Qorri, M. Marchetti, M. Di Carmine, D. Amuso

Department of Innovative Technology in Medicine and Dentistry, University of Chieti-Pescara, Chieti, Italy. ascarano@unich.it


OBJECTIVE: The purpose of the present clinical study is to assess the effectiveness of a lipolytic solution containing sodium salt of ascorbic acid at 0.24% and a surfactant agent at 0.020% ascorbyl-palmitate (SAP) for the treatment of double chin.

PATIENTS AND METHODS: A total of 10 healthy adult subjects affected by double chin (8 female and 2 male) were evaluated in the present investigation. The patients were admitted to a total of 4 sessions, with biweekly procedures, without no other active agents addiction.

RESULTS: In all the subjects a reduction of the convexity of the chin after the treatment with SAP was observed. Improvement in submental appearance was achieved in 90% (9/10) of the patients. One patient did not see any improvement in submental appearance after two section treatments and withdrew from the treatment.

CONCLUSIONS: In conclusion, in the present study, a new adipocytolytic solution consisting of sodium ascorbate mixed with ascorbyl-palmitate was used with success as a surfactant agent for the treatment of double chin.

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A. Scarano, R. Amore, A. Greco Lucchina, E. Qorri, M. Marchetti, M. Di Carmine, D. Amuso
Reduction of double chin without surgery using ascorbic acid and ascorbyl-palmitate solution: a clinical study

Eur Rev Med Pharmacol Sci
Year: 2023
Vol. 27 - N. 3 Suppl
Pages: 109-113
DOI: 10.26355/eurrev_202304_31327