Eur Rev Med Pharmacol Sci 2023; 27 (5): 1985-1988
DOI: 10.26355/eurrev_202303_31563

Prognosis of direct pregnancy in untreated atypical endometrial hyperplasia: a case report

L.-Y. Zuo, F.-F. Liu, L. Tian, J.-L. Wang

Department of Obstetrics and Gynecology, Department of Pathology, Reproductive Medical Center, Peking University People’s Hospital, Beijing, China. tianli916916@126.com


BACKGROUND: An increasing number of atypical endometrial hyperplasia (AEH) or endometrial cancer (EC) patients with fertility requirements choose conservative management, such as oral high-dose progesterone. Most of them use assisted reproductive technology (ART) to become pregnant after experiencing remission. However, the outcome of pregnancy is not ideal, probably because of long-term drug application in large doses or invasive uterine cavity treatment.

CASE REPORT: We presented a case of AEH who underwent direct pregnancy with good results without any treatment for her pathological endometrium. We described her endometrial histological results pre-and post-pregnancy in detail, hitherto absent from reports on this topic.

CONCLUSIONS: Patients with a strong desire to bear children at the time of an AEH diagnosis could consider taking 1-2 years to try a pregnancy before treating their AEH.

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To cite this article

L.-Y. Zuo, F.-F. Liu, L. Tian, J.-L. Wang
Prognosis of direct pregnancy in untreated atypical endometrial hyperplasia: a case report

Eur Rev Med Pharmacol Sci
Year: 2023
Vol. 27 - N. 5
Pages: 1985-1988
DOI: 10.26355/eurrev_202303_31563