Clinical outcome of coronary artery bypass grafting (CABG) in hemodialysis-dependent patients and comparison with non-renal failure patients

Sh. Ziabakhsh Tabary, M. Fazli

Mazandaran Heart Center, Mazandaran University of Medical Sciences, Sari, Iran. mehran222@gmail.com

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• Cardiology

BACKGROUND: Coronary artery bypass grafting (CABG) is a revascularization technique that has been reported as having satisfactory survival rates in Hemodialysis (HD) dependent patients.
AIM: The aim of this study was to determine morbidity and mortality of isolated CABG in HD-dependent patients and compare with non- renal failure (RF) patients.

PATIENTS AND METHODS: We performed a retrospective analysis of data related to all patients who underwent first time, on-pump, isolated CABG surgery between May 23, 2004 to September 22, 2012, we selected 32 CRF patients with history of chronic hemodialysis (group HD) and 32 non renal failure patients (group non-HD). The preoperative data of two groups were matched completely. We collected all data of intraoperative and postoperative. Data were analyzed by SPSS version 16.

RESULTS: the mean age of HD group and non-HD group were 52.46±3.24 and 52.12±3.54 years (p = 0.68). Low cardiac output syndrome was occurred in 4 patients (12.5%) of HD group and one patient (3.12%) of non-HD group (p = 0.16). 96.87% of patients in HD group and 81.25% of patient in non-HD group (p = 0.045) needed infusion of packed cell. 31.25% in HD group and 6.25% in non-HD group needed platelets infusion (p = 0.010). Infection was observed in 9.37% of HD group and 3.12% of non-HD group patients (p = 0.30). The hospital stay in HD group was 15.21±2.63 days and in non-HD group was 5.93±0.94 days (p = 0.000). Finally, we have 2 death (6.25%) in HD-dependent patients.

CONCLUSIONS: Isolated on-pump CABG in HD patients compared with non-HD patients was associated with high rate of morbidity and longer hospitalization.

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