Eur Rev Med Pharmacol Sci 2014; 18 (17): 2419-2423

Early ultrasonographic diagnosis of placental mesenchymal dysplasia

S. Gerli, C. Giordano, R. Del Sordo, D. Fratini, G.C. Di Renzo

Department of Surgical and Biomedical Sciences, Division of Obstetrics and Gynecology, University of Perugia, Perugia, Italy. sandro.gerli@unipg.it


Placental mesenchymal dysplasia (PMD) is a rare pathology characterized by vascular anomalies, placentomegaly and grapelike vesicles resembling partial molar pregnancy. PMD is often associated with fetal growth restriction or intrauterine fetal demise.

We report a case of an early diagnosis of PMD at 10 weeks’ gestation, with a regular intrauterine growth and a fetal demise occurring at 31 week’s gestation. The placenta showed aneurysmally dilated and tortuous vessels with luminal thrombosis.
Even in presence of a regular fetal growth, a fetal demise may always occur, suggesting the option of an early heparin administration to reduce the risk of thrombosis of chorionic vessels.

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To cite this article

S. Gerli, C. Giordano, R. Del Sordo, D. Fratini, G.C. Di Renzo
Early ultrasonographic diagnosis of placental mesenchymal dysplasia

Eur Rev Med Pharmacol Sci
Year: 2014
Vol. 18 - N. 17
Pages: 2419-2423