Serum uric acid level predicts new-onset atrial fibrillation after coronary artery bypass graft operation

M.E. Memetoglu, T. Kehlibar, M. Yılmaz, R. Günay, Y. Arslan, A. Tuygun, C. Kocaaslan, G. Çoskun, B. Ketenci, M.R. Güney, M. Demirtas

Cardiovascular Surgery Department, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, Istanbul, Turkey. dr.m.erdem07@hotmail.com

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• Cardiology

OBJECTIVE: To investigate the association between serum uric acid levels and the risk of incident atrial fibrillation in patients after coronary artery bypass graft (cABG) operation.

PATIENTS AND METHODS: A total of 174 patients undergoing nonemergency coronary artery bypass graft operation were included in the study. Patients with previous atrial arrhythmia or requiring concomitant valve surgery were excluded. We prospectively analyzed 174 patients (mean age: 59.8 years; 109 male and 65 female). The serum uric acid level was determined preoperatively.

RESULTS: After a coronary artery bypass graft operation operation, 35 (20%) patients developed atrial fibrillation. Preoperative uric acid levels were significantly higher in patients who developed atrial fibrillation than in those who did not (7.8 ± 1.1 vs 5 ± 0.9). Using a cutpoint of 6.55, the preoperative level correlated with the appearance of atrial fibrillation with a sensitivity of 91.4% and specificity of 84.2%.

CONCLUSIONS: Serum uric acid level can increase the sensitivity and specificity in predicting atrial fibrillation in patients after CABG operation.

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