Retraction Note: A multicenter clinical study with myo-inositol and alpha-lactalbumin in Mexican and Italian PCOS patients

I. Hernandez Marin, O. Picconi, A.S. Laganà, L. Costabile, V. Unfer

Human Reproduction Department, Hospital Juárez de México, México City, Mexico; Facultad de Medicina, Universidad Nacional Autónoma De México (UNAM), México City, México

---

• Retraction Note

The article “A multicenter clinical study with myo-inositol and alpha-lactalbumin in Mexican and Italian PCOS patients” by I. Hernandez Marin, O. Picconi, A.S. Laganà, L. Costabile, V. Unfer, published in Eur Rev Med Pharmacol Sci 2021; 25 (8): 3316-3324–DOI: 10.26355/eurrev_202104_25743–PMID: 33928619, has been retracted by the Publisher and the Editor in Chief.

Following concerns raised by a whistleblower regarding ethics approval issues, statistical analysis, the reliability of the reported results, and potential conflicts of interest, the journal initiated an editorial investigation in accordance with journal policies and COPE guidelines.

The authors were contacted and provided a response as well as the original data. An independent statistical expert was appointed to reassess the manuscript.

The evaluation identified insufficient documentation of ethics approval across all participating centers and unresolved methodological and statistical concerns, which together limit the reliability and interpretability of the reported findings.

In light of these issues, the Editor-in-Chief has concluded that the article’s results and conclusions are compromised. The article is therefore retracted.

The authors have been informed of this decision and do not agree with the retraction.

This article has been retracted. The Publisher apologizes for any inconvenience this may cause.